Active Studies

The Department of Pediatric Urology at DMC Children’s Hospital of Michigan currently have several studies that are recruiting participants at this time. For more information, or to refer a patient, please contact us at (313) 745-5588.

1. Bedwetting and Sleep-Disordered Breathing

Bedwetting is very stressful, causing shame and unhappiness in children and their families. Children are often bothered although they may not show it. We know that many children don’t outgrow bedwetting unless they get help. Swollen tonsils can cause breathing problems in sleep (such as snoring and paused breathing or apnea), and this may cause bedwetting. Tonsil removal surgery may help sleep breathing problems and bedwetting go away.  In a recent study, we conducted a phone interview in parents of children who had tonsil removal surgery, and found out that half of these children had their bedwetting go away. However, we don’t know how it works and why it works in some children and not in others. In this current study we are trying to answer these questions.

2. Effects of Parenting a Child with a Disorder of Sex Development (DSD)

While there has been some research on how children with Disorders of Sex Development are affected by their condition, very little is known about their parents. The Department of Pediatric Urology at the Children's Hospital of Michigan is part of  a group of six hospitals working together to collect data on how parents respond to their child’s diagnosis and how they are affected, in terms of symptoms of anxiety, depression, and stress. We are interested in figuring out which parents are at greatest risk for difficulties so that interventions can be created to offer to these parents

3. Stress Related to Having a Child with Voiding Problems and/or Bedwetting

Having a child with voiding problems and/or bedwetting can be very frustrating for parents. Additionally, many of these children also have behavioral problems and diagnoses such as Attention Deficit Hyperactivity Disorder (ADHD), which can make parenting them even more difficult. This study is examining how parents are affected, by gathering information on their level of stress and symptoms of depression and anxiety. Information is also being collected on the children, with regard to their medical treatment to determine which aspects of the child’s voiding problems and/or bedwetting are most frustrating/stressful for parents.

4. Study of Brain Development in Girls with Congenital Adrenal Hyperplasia (

Girls with CAH are exposed to different types of hormones during their mother’s pregnancy than girls without CAH. This study will use cutting-edge technology to examine whether these different hormones have affected brain development in girls with CAH. As adults, women with CAH have higher levels of depression, anxiety, and suicidal thoughts. We are interested in learning whether differences in brain development may help to explain this trend. The study is funded by the Children's Hospital of Michigan Foundation.  

5. Screening and Diagnostic Markers in Children with Stones: Is Proteomics the Answer?

This is a pilot study designed to identify the proteins in the urine that are unique to children with stones. The identified protein (s) in urine may serve as biomarkers for prevention and early diagnosis of stones, allowing earlier intervention and avoiding complications such as kidney damage. The study is funded by the Children's Hospital of Michigan Foundation.